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10 Best Cat Urine Enzymatic Cleaner 2025 in the United States
#1
Winner
Rocco & Roxie Stain & Odor Eliminator for Strong Odor, 32oz Enzyme Pet Odor Eliminator for Home, Carpet Stain Remover for Cats & Dog Pee, Enzymatic Cat Urine Destroyer, Carpet Cleaner Spray
The Rocco & Roxie Supply Co. Stain & Odor Eliminator is a strong contender in the category of enzymatic cleaners for cat urine and other pet-related stains. Its enzyme formula is key to its effectiveness, as it works by breaking down odors and stains at a deep level, ensuring a thorough clean. This makes it particularly suitable for pet owners looking to tackle strong odors from urine, feces, or even vomit without harsh chemicals. One of its biggest advantages is that it's certified safe for use around pets and children, being chlorine-free and color-safe, which provides peace of mind when cleaning in family spaces.
Customer Highlights
A summary of real customer reviews to highlight what shoppers are saying!Customer Highlights
A summary of real customer reviews to highlight what shoppers are saying!#2
ANGRY ORANGE Pet Odor Eliminator for Cat Urine and Smells - Fresh Scent - 24 oz
The ANGRY ORANGE Pet Odor Eliminator for Cat Urine and Smells is a popular choice in the pet supplies category, with a best sellers rank to back it up. This product comes in a 24 oz spray form and features a fresh scent, which is a pleasant alternative to the typical chemical smells found in many cleaners. The enzyme formula is designed to break down cat urine effectively, making it a strong contender for tackling stubborn pet odors.
Customer Highlights
A summary of real customer reviews to highlight what shoppers are saying!Customer Highlights
A summary of real customer reviews to highlight what shoppers are saying!#3
Angry Orange Stain Remover - 32oz Enzyme Pet Cleaner - Dog & Cat Urine Destroyer and Stain Remover - Citrus Spray Cleaning Solution - Puppy Supplies
The Angry Orange Stain Remover is a dual-action enzyme cleaner designed to eliminate pet odors and stains, including those from cat urine. It uses a powerful enzyme formula that tackles smells and stains at their source, ensuring long-lasting freshness for up to 80 hours. This product is versatile and can be used on a variety of surfaces such as carpets, hardwood floors, and fabrics.
Customer Highlights
A summary of real customer reviews to highlight what shoppers are saying!Customer Highlights
A summary of real customer reviews to highlight what shoppers are saying!Top 10 Best Cat Urine Enzymatic Cleaner 2025 in the United States
#1
Winner
9.7 score
Rocco & Roxie Stain & Odor Eliminator for Strong Odor, 32oz Enzyme Pet Odor Eliminator for Home, Carpet Stain Remover for Cats & Dog Pee, Enzymatic Cat Urine Destroyer, Carpet Cleaner Spray
Rocco & Roxie Stain & Odor Eliminator for Strong Odor, 32oz Enzyme Pet Odor Eliminator for Home, Carpet Stain Remover for Cats & Dog Pee, Enzymatic Cat Urine Destroyer, Carpet Cleaner Spray
Enzyme Formula: Breaks down odors and stains
Surface Compatibility: Carpets, floors, furniture, pet areas
Scent: Original
Drying Time: Varies
Eco-Friendliness: Eco-friendly
Chosen by 1364 this week
ANGRY ORANGE Pet Odor Eliminator for Cat Urine and Smells - Fresh Scent - 24 oz
ANGRY ORANGE Pet Odor Eliminator for Cat Urine and Smells - Fresh Scent - 24 oz
Enzyme Formula: Breaks down cat urine effectively
Scent: Fresh
Application Method: Spray
Angry Orange Stain Remover - 32oz Enzyme Pet Cleaner - Dog & Cat Urine Destroyer and Stain Remover - Citrus Spray Cleaning Solution - Puppy Supplies
Angry Orange Stain Remover - 32oz Enzyme Pet Cleaner - Dog & Cat Urine Destroyer and Stain Remover - Citrus Spray Cleaning Solution - Puppy Supplies
Enzyme Formula: dual-action cleaner
Surface Compatibility: carpets, hardwood, fabrics
Scent: Citrus
Application Method: Spray
Angry Orange Pet Odor Eliminator for Home - 8oz Dog and Cat Pee Smell Remover for Carpet, Grass, Tile and Furniture - Citrus Concentrate, Makes 128oz of Liquid
Angry Orange Pet Odor Eliminator for Home - 8oz Dog and Cat Pee Smell Remover for Carpet, Grass, Tile and Furniture - Citrus Concentrate, Makes 128oz of Liquid
Enzyme Formula: Yes
Surface Compatibility: Carpets, tiles, grass
Scent: Fresh Orange Blast
Application Method: Mixing
Simple Solution Extreme Pet Stain and Odor Remover | Enzymatic Cleaner with 3X Pro-Bacteria Cleaning Power | 1 Gallon , 128 Fl Oz (Pack of 1)
Simple Solution Extreme Pet Stain and Odor Remover | Enzymatic Cleaner with 3X Pro-Bacteria Cleaning Power | 1 Gallon , 128 Fl Oz (Pack of 1)
Enzyme Formula: Three times stronger than regular cleaners
Surface Compatibility: Carpets, upholstery, fabric toys
Application Method: Saturate, wait, blot dry
Drying Time: A few minutes
Eco-Friendliness: Safe around children and pets
Related Products
Up to 6% off
Nature's Miracle Urine Destroyer Plus for Cats, Enzymatic Formula for Severe Cat Urine Stains, 32 oz
Nature's Miracle Urine Destroyer Plus for Cats, Enzymatic Formula for Severe Cat Urine Stains, 32 oz
Enzyme Formula: Enzymatic formula
Surface Compatibility: Safe for various environments
Scent: Unscented
Application Method: Spray
Drying Time: 15 minutes
Eco-Friendliness: 25% recycled material
Pet Odor and Stain Eliminator - 32 oz ACTIVE Enzyme Cleaner for Dog & Cat Urine, Stain Remover Spray for Carpet, Upholstery, Hardwood, Spot Cleaning, Deodorizer for Dogs Cats Pets - Natural Citrus Oil
Pet Odor and Stain Eliminator - 32 oz ACTIVE Enzyme Cleaner for Dog & Cat Urine, Stain Remover Spray for Carpet, Upholstery, Hardwood, Spot Cleaning, Deodorizer for Dogs Cats Pets - Natural Citrus Oil
Enzyme Formula: Breaks down pet urine, poop, vomit
Surface Compatibility: Carpets, upholstery, hardwood floors, furniture
Scent: Citrus, Natural Citrus Oil
Application Method: Spraying
Eco-Friendliness: Natural ingredients, safe for pets, children
Nature's Miracle Advanced Cat Stain and Odor Eliminator Spray, Severe Mess Enzymatic Formula, 32 fl oz
Nature's Miracle Advanced Cat Stain and Odor Eliminator Spray, Severe Mess Enzymatic Formula, 32 fl oz
Enzyme Formula: Powerful enzymatic formula
Surface Compatibility: Most surfaces including carpets, floors
Scent: Fresh
Application Method: Liquid spray
Drying Time: Varies by liquid amount and surface
Nature’s Miracle Set-In Stain Destroyer, For Cat Messes, Oxy Formula With Orange Scent, 1 Gallon
Nature’s Miracle Set-In Stain Destroyer, For Cat Messes, Oxy Formula With Orange Scent, 1 Gallon
Enzyme Formula: Oxy Formula
Surface Compatibility: variety of surfaces
Scent: light orange
Application Method: straightforward
Eco-Friendliness: safe around pets when used correctly
#10
7.1 score
Nature's Miracle Stain and Odor Remover Cat, Odor Control Formula, Pour
Nature's Miracle Stain and Odor Remover Cat, Odor Control Formula, Pour
Enzyme Formula: Enzymatic cleaner
Surface Compatibility: Carpets, floors, furniture, fabrics
Scent: Citrus
Application Method: Pour, wait 10 minutes, blot
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Buying Guide for the Best Cat Urine Enzymatic Cleaner
Choosing the right cat urine enzymatic cleaner is essential for effectively removing stains and odors caused by cat urine. Enzymatic cleaners work by breaking down the proteins in urine, which helps to eliminate the smell and prevent your cat from returning to the same spot. When selecting a cleaner, it's important to consider several key specifications to ensure you get the best product for your needs.Enzyme FormulaThe enzyme formula is the core component of an enzymatic cleaner. It contains specific enzymes that break down the proteins in cat urine, effectively removing the odor and stain. A strong enzyme formula is crucial for thorough cleaning. Look for products that specifically mention they target cat urine, as these will have the right enzymes for the job. If you have multiple pets or persistent stains, opt for a cleaner with a more concentrated enzyme formula.
Surface CompatibilitySurface compatibility refers to the types of surfaces the cleaner can be used on, such as carpets, upholstery, hardwood floors, and tiles. It's important to choose a cleaner that is safe for the surfaces you need to treat. Some cleaners are versatile and can be used on multiple surfaces, while others are designed for specific materials. If you need to clean various surfaces, a multi-surface cleaner is a good choice. Always check the label to ensure the cleaner won't damage your floors or furniture.
ScentThe scent of the cleaner can affect your overall experience. Some enzymatic cleaners have a strong fragrance to mask the odor of urine, while others are unscented or have a mild scent. If you or your pets are sensitive to strong smells, an unscented or lightly scented cleaner may be preferable. On the other hand, if you want to leave a fresh scent behind, choose a cleaner with a fragrance you find pleasant. Consider your personal preference and any sensitivities when selecting the scent.
Application MethodThe application method refers to how the cleaner is applied to the affected area. Common methods include spray bottles, pour bottles, and foam applicators. Spray bottles are convenient for spot cleaning and small areas, while pour bottles are useful for larger stains. Foam applicators can help the cleaner penetrate deeper into carpets and upholstery. Choose an application method that suits the size and type of the stains you need to treat. For ease of use, a spray bottle is often the most versatile option.
Drying TimeDrying time is the amount of time it takes for the cleaner to dry after application. This can vary depending on the product and the surface being treated. Faster drying times are more convenient, especially if you need to use the area soon after cleaning. However, some cleaners may require a longer drying time to ensure the enzymes fully break down the urine proteins. Consider how quickly you need the area to be usable again and choose a cleaner with an appropriate drying time for your needs.
Eco-FriendlinessEco-friendliness refers to the environmental impact of the cleaner. Eco-friendly enzymatic cleaners are made with biodegradable ingredients and are free from harsh chemicals that can harm the environment. If you are environmentally conscious, look for products labeled as eco-friendly or biodegradable. These cleaners are safer for the environment and often safer for your pets and family as well. Choosing an eco-friendly cleaner can help reduce your environmental footprint while effectively cleaning up cat urine.